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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VPS13C
All Species:
10.91
Human Site:
S2468
Identified Species:
30
UniProt:
Q709C8
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q709C8
NP_001018098.1
3753
422390
S2468
N
L
E
L
E
Y
A
S
M
V
P
S
S
Q
G
Chimpanzee
Pan troglodytes
XP_510458
3836
431033
S2551
N
L
E
L
E
Y
A
S
M
V
P
S
S
Q
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851912
3629
408076
L2443
K
V
Q
P
N
H
S
L
R
V
I
G
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BX70
3748
420070
S2463
H
L
E
L
D
Y
A
S
L
E
P
S
R
Q
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511058
3801
426177
I2507
T
L
E
L
D
Y
S
I
S
E
P
M
H
R
G
Chicken
Gallus gallus
XP_001233000
3758
422392
V2470
N
M
E
L
E
Y
S
V
F
E
A
P
Q
R
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922767
3699
412330
Y2445
D
K
S
L
D
L
E
Y
S
S
F
E
R
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001192977
2470
271032
T1296
D
K
P
V
D
I
Y
T
R
D
S
T
I
V
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q07878
3144
357831
C1969
N
V
H
N
R
I
V
C
E
A
R
C
D
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.9
N.A.
87
N.A.
86.4
N.A.
N.A.
77.2
68.7
N.A.
59.6
N.A.
N.A.
N.A.
N.A.
24.1
Protein Similarity:
100
97.4
N.A.
92
N.A.
93.3
N.A.
N.A.
87.6
82.9
N.A.
76.8
N.A.
N.A.
N.A.
N.A.
41
P-Site Identity:
100
100
N.A.
20
N.A.
66.6
N.A.
N.A.
40
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
N.A.
46.6
N.A.
86.6
N.A.
N.A.
60
53.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
34
0
0
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% C
% Asp:
23
0
0
0
45
0
0
0
0
12
0
0
12
0
0
% D
% Glu:
0
0
56
0
34
0
12
0
12
34
0
12
0
12
0
% E
% Phe:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
56
% G
% His:
12
0
12
0
0
12
0
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
23
0
12
0
0
12
0
12
0
0
% I
% Lys:
12
23
0
0
0
0
0
0
0
0
0
0
0
0
12
% K
% Leu:
0
45
0
67
0
12
0
12
12
0
0
0
0
0
0
% L
% Met:
0
12
0
0
0
0
0
0
23
0
0
12
0
0
0
% M
% Asn:
45
0
0
12
12
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
0
12
12
0
0
0
0
0
0
45
12
0
12
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
0
0
0
12
34
0
% Q
% Arg:
0
0
0
0
12
0
0
0
23
0
12
0
23
23
12
% R
% Ser:
0
0
12
0
0
0
34
34
23
12
12
34
34
12
12
% S
% Thr:
12
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% T
% Val:
0
23
0
12
0
0
12
12
0
34
0
0
0
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
56
12
12
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _